General Chapters related to compounding establish procedures, methods and practices that help ensure the quality of compounded preparations and also provide criteria for safe handling of medications.
Together these General Chapters help safeguard patient and practitioner safety.
According to the American Medical Association, the beyond-use date on a medication's label should be no later than the expiration date on the manufacturer’s container and the medication should not be used after the beyond-use date.
The FDA says it's dangerous to take medications after their expiration date because they may not be as effective, their chemical composition may have changed, or they may have deteriorated to a point where harmful bacteria could breed.
Beyond use dates are used for compounded preparations and are generally in days or months.
The major problem for pharmacists is that the stability of compounded formulations often is not known.
The beyond-use date is determined by the pharmacy when they fill a prescription based on different factors, including: The beyond-use date is almost always different than the actual expiration date of the drug.
Expiration dates are required on commercially manufactured products and are determined after extensive study of the product's stability.
Most expiration dates are given in years for commercial products.
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Beyond use dates should be in accordance with the manufacturer's approved labeling.